{"product_id":"allergy-research-group-pregnenolone-100-hormone-support-60-tablets","title":"Allergy Research Group Pregnenolone 100 Hormone Support 60 tablets","description":"\u003cp\u003eMicronized pregnenolone to support cognitive function, mood, stress resilience, and healthy hormone synthesis.*\u003cbr\u003eWhat It Does\u003cbr\u003ePregnenolone is a neurosteroid and hormone precursor that plays a vital role in the production of cortisol, progesterone, estrogen, testosterone, and other steroid hormones.* It may support mood, focus, memory, and the body’s adaptive response to stress as levels decline with age.*\u003cbr\u003eHow It Works\u003cbr\u003e•    Pregnenolone (Micronized): A bioavailable form of the parent steroid hormone that supports adrenal, reproductive, and neurological function.*[1]\u003cbr\u003e•    Neurosteroid Activity: Synthesized in the brain and peripheral nervous system, pregnenolone modulates GABA and NMDA receptors and influences neuroplasticity via BDNF.*[2,3,4,5]\u003cbr\u003e•    Hormone Precursor: Serves as the first step in the synthesis of key hormones including cortisol and sex hormones, influencing metabolism, immune balance, and reproductive health.*[1,6]\u003cbr\u003e•    Cognitive and Mood Support: Clinical trials suggest pregnenolone supplementation supports focus, working memory, and mood, particularly in populations under cognitive or emotional strain.*[7,8,9]\u003cbr\u003e•    Age-Related Decline: Endogenous pregnenolone production decreases with age, potentially contributing to changes in mental clarity and resilience.*[6,10]\u003cbr\u003e•    Clinical Dosing Evidence: Human studies have used 30–500 mg daily to support quality of life, attention, and cognitive performance in targeted populations.*[7,8,9]\u003cbr\u003eWho It’s For\u003cbr\u003eIdeal for adults seeking support for healthy mood, memory, cognitive function, or hormonal balance, especially during periods of mental fatigue, aging, or stress.*\u003cbr\u003eSpecial Features\u003cbr\u003eARG offers Pregnenolone (micronized) for enhanced bioavailability in 50 mg and 100 mg strength options to accommodate individualized, evidence-informed protocols.*\u003cbr\u003ePregnenolone helps bridge the gap between hormone synthesis and brain health, supporting multiple systems through a foundational neurosteroid pathway.*\u003cbr\u003eReferences\u003cbr\u003e1.    Murugan S, et al. J Biol Chem. 2019;294(12):4596–607.\u003cbr\u003e2.    Mathis C, et al. Psychopharmacology (Berl). 1994;116(2):201–6.\u003cbr\u003e3.    Mathis C, et al. Neuropharmacology. 1996;35(8):1057–64.\u003cbr\u003e4.    Pierce SR, et al. Mol Pharmacol. 2022;101(2):68–77.\u003cbr\u003e5.    Charalampopoulos I, et al. Ann N Y Acad Sci. 2006;1088:139–52.\u003cbr\u003e6.    Vallee M, et al. Brain Res Brain Res Rev. 2001;37(1–3):301–12.\u003cbr\u003e7.    Naylor JC, et al. JAMA Netw Open. 2020;3(3):e200287. doi:10.1001\/jamanetworkopen.2020.0287\u003cbr\u003e8.    Kreinin A, et al. Clin Schizophr Relat Psychoses. 2017;10(4):201–10.\u003cbr\u003e9.    Ritsner MS, et al. J Clin Psychiatry. 2010;71(10):1351–62.\u003cbr\u003e10.    Naert G, et al. Psychoneuroendocrinology. 2007;32(8–10):1062–78.\u003c\/p\u003e","brand":"Pura Vida Wellness Company","offers":[{"title":"Default Title","offer_id":67682662744255,"sku":null,"price":46.79,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0762\/2531\/5007\/files\/1000_front_c891511f-2b90-4ab9-b0aa-9b7966c5e4df.png?v=1792157773","url":"https:\/\/www.puravidawellnesscompany.com\/products\/allergy-research-group-pregnenolone-100-hormone-support-60-tablets","provider":"Pura Vida Wellness Company","version":"1.0","type":"link"}